A Secret Weapon For ceesdekker.net
A Secret Weapon For ceesdekker.net
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Rotary movement of DNA rotors on nanopores. Leading row: Uncooked video clip of the Cy5 channel of every rotor. Middle row: corresponding solitary-particle localization outcomes of both of those ends of your DNA rotors. The placement of the current body is marked as orange and blue dots, and also the trajectory of The ten frames prior to The existing frame is revealed as reliable lines.
1996, to start with mesoscopic charge density waves products; and first electrical measurements on an individual metallic nanocluster between nanoelectrodes
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Non-equilibrium folding of person DNA molecules recaptured as much as 1000 times in a solid point out nanopore
2010, formulated a new way (‘wedging transfer’) to manipulate nanostructures; very first report of DNA translocation by way of graphene nanopores; and recognized hybrid nanopores by directed insertion of α-hemolysin into stable-point out nanopores
Cornelis (Cees) Dekker (Haren, seven april 1959) is een Nederlandse natuurkundige en universiteitshoogleraar verbonden aan de Technische Universiteit Delft. Van 2010 tot en met 2018 was hij tevens directeur van het Kavli Institute of Nanoscience in Delft. Zijn vakgebied is de moleculaire biofysica; hierbij beweegt hij zich op het grensvlak van de natuurkunde en de biologie waarbij hij gebruikmaakt van de zogeheten nanotechnologie, de technieken om aan enkele atomen en moleculen te kunnen meten.
We use nanofabricated microfluidic buildings to sample spatial boundaries for microorganisms and biomimetic vesicles with reconstituted protein networks and this assess the basic role of spatial confinement for the molecular and cellular level. Our assignments involve the subsequent:
Instance (one) of bending configurations in 3D simulations of DNA rods on ceesdekker.net nanopores. A part of the membrane is revealed in grey, the rim with the pore is highlighted in crimson, in addition to a 3D rendering on the movement in the DNA rod is exhibited.
The rotors harness Power from the nanoscale drinking water and ion movement that is created by a static chemical or electrochemical likely gradient within the nanopore, which are founded by way of a salt gradient or applied voltage, respectively. These synthetic nanoengines self-organize and work autonomously in physiological problems, suggesting methods to developing Strength-transducing motors at nanoscale interfaces.
Resolving the stage measurement in condensin-driven DNA loop extrusion identifies ATP binding since the stage-producing course of action
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Nanoscientist Cees Dekker is undoubtedly an amiable and flamboyant gentleman who appears much young when compared to the sixty two several years he truly is – fashionable Eyeglasses, psychedelic shirt, participating smile – but not one to squander time. He normally takes his time, but no more than necessary.
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Instance (two) of bending configurations in 3D simulations of DNA rods on nanopores. A part of the membrane is revealed in grey, the rim of your pore is highlighted in crimson, in addition to a 3D rendering on the movement on the DNA rod is exhibited.